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HGF administration promotes the migration and proliferation of cultured SCs and induces the expression of various neurotrophic factors (Ko et al., 2018)

With advancements in sequencing technologies, genome-wide methylation profiling is now feasible in both brain and peripheral tissues

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BPC-157 demonstrates exceptional safety in animal toxicology studies, with comprehensive evaluations in mice, rats, rabbits, and dogs failing to establish a lethal dose (LD) across wide dose ranges extending from standard research doses (6 g/kg) to levels exceeding 1000-fold higher concentrations (20 mg/kg), with no evidence of acute toxicity, organ-specific damage, or systemic adverse effects even following repeated high-dose administration