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Figure S3: Vitamin B12 deficiency may cause or be associated with signs and symptoms in multiple organ systems

Therefore, the fact that vB12 treatment of Tbx1 +/ mice restored glutamate and inosine to WT levels is consistent with their metabolic relatedness and their dependence upon mitochondrial activity, which is responsive to vB12

It is entirely free from synthetic additives, artificial colors, flavors, or preservatives, ensuring that you receive only the most natural and beneficial form of Vitamin B12

It is found that these two markers started to increase even when B12 level was still above its lower limit of 148 pmol/L (200 pg/L), as such they are considered as more sensitive markers and may help for diagnosis of B12 deficiency