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Results: A total of 84 patients that were ever treated with givosiran were enrolled (acute intermittent porphyria, N=75

Vitamin C, zinc, and copper all play roles in collagen formation

Sulfhydryl group of cysteine can be considered also as a very strong reducing factor, which is very important for activity of many proteins, a oligopeptides (glutathione), has a strong influence on redox potential of environment in certain compartments in vivo, and can form a center of the active site of some enzymes (e.g

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Coronin 2A (CORO2A) is a WD repeat protein family member that facilitates the formation of multi-protein complexes involved in a variety of cellular processes, including actin microfilaments, endosomal fission, and clathrin-dependent cargo uptake