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Tyrosine hydroxylase is the critical enzyme in the synthesis of epinephrine, norepinephrine and dopamine, and tryptophan hydroxylase is the essential enzyme in the synthesis of serotonin

N-acetylcysteine alleviated tris(2-chloroisopropyl) phosphate-induced sperm motility decline and functional dysfunction in mice through reversing oxidative stress and DNA damage

Miyamoto R, Takigawa H, Yuge R, Shimizu D,Ariyoshi M, Otani R, Tsuboi A,Tanaka H, Yamashita K,Hiyama Y

Additionally, carvacrol and cilostazol co-administration was found to ameliorate ethanol-induced liver fibrosis through the SIRT1/Nrf2/HO-1 pathway, exerting antioxidant, anti-inflammatory, and anti-apoptotic effects ( Lastly, biliary senescence and hepatic fibrosis are central features of cholangiopathies, such as primary sclerosing cholangitis (PSC)