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each dispensing requires a new written or electronic prescription from a licensed provider

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ROS, whether directly or through the formation of lipid peroxidation products such as 4-hydroxy-2-nonanal, may play a role in enhancing inflammation by activating stress kinases (JNK, MAPK, p38) and redox-sensitive transcription factors such as NF-B and AP-1 (Rahman and MacNee, 2000)