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This rate limiting step is controlled by the cellular availability of cysteine and GCL activity

Conventional antidepressants have decades of human research showing they actually work in people

However, synaptic activity drives the maturation of inhibitory neurotransmission and results in stable and functionally stronger GABAergic synapses compared with those observed during the early phases of inhibitory synaptogenesis (Dobie and Craig, 2011

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