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At the cellular level, drug delivery, such as through capillary pressure microinjection, may suffer from instability in administration speed, leading to uneven or unstable drug distribution within cells, thereby affecting drug stability and bioavailability [121]

In comparing Adh-F homozygotes (wild-type) and Adh- nulls (homozygous null), research has shown that Adh- nulls have a lower level of tolerance for ethanol, starting the process of intoxication earlier than its counter partner

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10.1016/j.reprotox.2007.07.010 149 VictorV