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showed that, while IFN- released by T cells initially induced LV immunosuppression, elevated T cell densities eventually dampened this effect and induced LEC apoptosis (204)

(Wu et al., 2019) demonstrated in human umbilical vein ECs and arteries of HHcy mice that Hcy triggers the expression of ER oxidoreductin-1 (Ero1), leading to ER stress and subsequent inflammation