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Description

Histamine is most known for its association with hay fever sufferers and being a mediator in allergic reactions and anaphylactic shock

However, little is known about the ability of PA to induce ferroptosis in TNBC cells

Jouan, Y

10.1139/H07-147 180 SajjadianF.RoshangarL.HemmatiA.NoriM.Soleimani-RadS.Soleimani-RadJ

For instance, oxidative stress disrupts redox-sensitive organelles, including the endoplasmic reticulum (ER) [9], leading to the accumulation of misfolded proteins, which triggers ER stress and impairs protein folding, modification, and transport [10]