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Although there are more and more animal experiments on UPS modulating renal diseases, further exploration of its specific mechanism is needed

Biomater Sci 11(15):53015319

DNA damage results in activation of ATM and ATR, which results in stabilization of the TP53 protein causing increased levels of cell cycle inhibitors, including CDKN1A/p21 Cip , CDKN1B/p27 Kip1 , and CDKN1C/p57 Kip2 [33]

In another particular embodiment, the diagnostic method of the invention comprises determining in a sample from a subject the levels of at least one marker as defined in Table 6

(no photo available) 96 tests $974 KT-64595 Isocitrate dehydrogenase ELISA Kit (ICD), Human For quantitative detection in human samples