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Vonk WI, Wijmenga C, Berger R et al (2010) Cu,Zn superoxide dismutase maturation and activity are regulated by COMMD1

Briefly, 100 L of cell-free supernatant from each well of a 24-well plate were transferred to a 96-well plate and 20 L of iodonitrotetrazolium chloride (4 mg/mL, Sigma-Aldrich) were added to each well

Since Vitamin B12 plays a significant role in DNA synthesis and cell production, its deficiency hampers the process, making the melanocytes susceptible to the damage

We accessed the GSE14668 and GSE96851 datasets from the Gene Expression Omnibus (GEO) database and focused on differentially expressed genes (DEGs), ferroptosis-related DEGs (FRGs) and autophagy-related DEGs (ARGs)