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This review further discusses the current understanding of genetic etiologies and altered physiology leading to disease, such as neuroinflammation, integrated stress response, aberrant proteostasis and mitochondrial dysfunction, among others

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The traditional classification of microglial phenotypes into binary M1 (pro-inflammatory) and M2 (anti-inflammatory/neuroprotective) categories has provided a useful conceptual framework, though it is increasingly recognized as an oversimplification of their functional diversity (Figure 5)

The antimicrobial effects of essential oils are manifested through the following mechanisms: a) rupturing the microbial cell wall or altering the phospholipid bilayer, leading to the expulsion of cell components

Walker et al, 2006