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doi: 10.1111/bcp.12804 135 Borowicz-ReuttKKCzuczwarSJ

2.9.1 Phase 1 A total of 48 female Mus musculus C57BL/6 (FMO3 +/+) strain WT mice, who were 8 weeks old, were divided into eight groups: six groups were based on the compound to be tested and the other two groups were, respectively, the positive control (FMC treatment) and the negative control (only phosphate-buffered saline treatment)

However, there are still issues to be resolved, such as the effectiveness of nanoparticles for targeted delivery, the safety of nanomaterials, and a dynamic monitoring system for antioxidant nanomedicine

Preclinical studies show no significant toxicity at therapeutic doses, with treated animals displaying no adverse behavioral changes or organ dysfunction