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Clinical Safety Profile of AOD-9604 in Obesity Treatment

Hooven LA, Sherman KA, Butcher S, Giebultowicz JM (2009) Does the clock make the poison

Lo et al., 2012

Unlike traditional drugs that have a broad effect on the immune system, biologics are designed to block specific inflammatory proteins, such as tumor necrosis factor-alpha (TNF-alpha), which plays a key role in many inflammatory conditions [5]

The binding of trivalent arsenicals to thiols in intracellular and cell surface proteins often results in aberrations of normal cellular processes including alteration of cellcell communication