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While the incorporation of free -tocopherol and -tocopherol acetate into alveolar macrophage membranes is limited in vitro , resulting in negligible impact on cellular activation, -tocopherol succinate exhibits enhanced solubility and rapid cellular uptake in vitro (Bulger and Maier, 2003)

Loss of the Nrf2 transcription factor causes a marked reduction in constitutive and inducible expression of the glutathione S-transferase Gsta1, Gsta2, Gstm1, Gstm2, Gstm3 and Gstm4 genes in the livers of male and female mice

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coagulans and/or inulin treated rats