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An imbalance between cellular oxidative and antioxidant systems, along with accumulation of oxidative damage and downregulation of Bcl2, can reduce the anti-apoptotic capacity of melanocytes, ultimately leading to hair greying [162]

The size, shape, and deformability of erythrocytes are crucial to their function, and abnormalities in these traits are seen in conditions like rheumatoid arthritis and T2DM

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Thromb Haemost 113:494504 Papp LV, Lu J, Holmgren A, Khanna KK (2007) From selenium to selenoproteins: synthesis, identity, and their role in human health