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CD8 + T cells release interferon- (IFN-), which downregulates the expression of SLC3A2 and SLC7A11, the two subunits of the System Xc , inhibiting cystine uptake by tumor cells and promoting ferroptosis (Wang et al

Taken together, we propose a model in which increased oxidative stress in TTR-V30M carriers, potentially promoted by misfolded TTR, contributes to reduced GSH availability [49, 50]

Herbal drug discovery for the treatment of nonalcoholic fatty liver disease

After the particles are phagocytosed, AMs move toward the middle and upper airways through cellular movement to be excreted by mucus clearance mechanisms [65]