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10.1161/atvbaha.118.311145 67 KattoorA

PARP1 plays the role of a cellular rheostat by gauging the level of ROS-inflicted DNA damage in the cell: if the number of clustered DNA lesions generated by ROS is rather moderate, then a small increase of PARP1 expression promotes base excision repair (BER) of the damaged DNA

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However, the authors examined the transplantation rate and urethral recovery of MSCs only one week after the rats had been injured during childbirth, and the long-term outcomes were not considered

Silvestri, I., Lyu, H., Fata, F., Boumis, G., Miele, A.E., Ardini, M., Ippoliti, R., Bellelli, A., Jadhav, A., Lea, W.A., Simeonov, A., Cheng, Q., Arner, E.S.J., Thatcher, G.R.J., Petukhov, P.A., Williams, D.L., Angelucci, F