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The mechanism lies in recruiting the chromatin remodeling protein CHD4 and reducing repressive histone marks (such as H3K9me3/H3K27me3) [32]

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She also directs the Computational Biology Laboratory, which she established in 2017 to develop and apply cutting-edge computational and AI-driven approaches to decode cancer ecosystems across space and time and translate these insights into clinically actionable biomarkers, predictive models, and therapeutic strategies

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Hosnedlova et al., 2018

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