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The transport of drug molecules from the nasal cavity to the brain involves two primary pathways: intracellular and extracellular

That is the administration route with the deepest published research basis for applications beyond the gastrointestinal tract

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Indeed, proteinuria is a key biomarker of kidney disease, as it predicts continued progressive functional decline of the kidney or a rapid drop in eGFR to 15 mL/min/1.73 m 2 , which marks end-stage kidney disease [17-19] , a condition that requires dialysis or a kidney transplant for survival

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