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Because PS-exposing cells are largely removed by spleen and can contribute to intravascular hemolysis and inflammatory vasculopathy, it is important to assess associated changes in vascular biomarkers (33, 41, 48)

Given the progressive nature of the disorder, disease pathogenesis is mainly triggered by continual processes such as geometric accumulation of oxidative radicals brought about by cellular inclusions and mitochondrial dysfunction 8,9,10

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Dec 28 2024;45(1):8.doi:10.1007/s00296-024-05770-7

Glutathione may help promote brighter and more even-toned skin by reducing oxidative stress and supporting healthy skin cells