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It also plays a key role in the synthesis of vitamins, including vitamins K and B12 (153)

Ageing Res Rev (2013) 12(1):37690

For lactate quantitation, samples (5 L, run in triplicate) were added to 115 L assay buffer containing 100 mM glycylglycine, 100 mM glutamate, 2 mM NAD, 1 U/mL lactate dehydrogenase, and 1 U/mL glutamate pyruvate transaminase, pH 8.5

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The mechanism of cellular damage is proposed to involve the reduction of free iron to Fe 2+ , followed by a Fenton-type reaction with H 2 O 2 to produce HO , that then oxidizes lipids and proteins [33]