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In addition, fatty acid synthase ( FASN ) and acetyl-CoA carboxylase ( ACC ) mRNA levels markedly increase during the dark (feeding) phase of WT mice, but not in PPAR KO mice, which instead exhibit persistently low expression levels (103)

[5] Mechanisms [edit] For GPCRs generally, each mechanism of homologous desensitization begins with receptor phosphorylation by an associated G protein-coupled receptor kinase (GRK)

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doi: 10.1017/S1751731120001068 220 MinL.ZhengN.ZhaoS.ChengJ.YangY.ZhangY.et al