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Clinical and preclinical literature suggest it modulates brainderived neurotrophic factor (BDNF) expression, enhances cholinergic and dopaminergic neurotransmission, and exhibits neuroprotective properties in models of cerebrovascular and cognitive impairment [2] [5]

Results: Heterozygous pathogenic mutations or any common polymorphisms in ATP8B1 , ABCB11 , ABCB4 or FXR were similarly frequent in patients and controls (8.97% vs

Interestingly, among all lophotrochozoans analyzed, some species may have experienced recent events of domain duplication and recruitment, respectively resulting in the STBD1 genes with more than one CBM20 copy and other functional domains

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It further regulates genes related to bile acid synthesis in the liver, such as Cyp7a1 , through the intestine-liver axis, ultimately exacerbating systemic metabolic disorder in diabetic mice ( Ruminococcus in the P.g -treated mouse group ( Ruminococcus species, such as Ruminococcus torques ( R.t ), possess direct vitamin D hydroxylation potential (Yamamoto and Jrgensen, 2019)