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Morrissey D, Sun Y, Koilpillai S, Kropf J, Carlan SJ

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Hydroxycarbamide versus chronic transfusion for maintenance of transcranial Doppler flow velocities in children with sickle cell anaemia-TCD with Transfusions Changing to Hydroxyurea (TWiTCH): a multicentre, open-label, phase 3, non-inferiority trial

Notably, the Wnt/-catenin signalling pathway is necessary for embryonic development and adult tissue homeostasis regeneration