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Pearle S, Zerwekh JE, Preminger GM et al (2015) Defining hypercalciuria in nephrolithiasis

Because of their high metabolic activity, the adrenal glands, which are required for the production of steroid hormones that regulate different physiological processes, are vulnerable to oxidative damage ( 4 Oxidative stresses Oxidative stress occurs when prooxidant molecules like ROS and reactive nitrogen species (RNS) get produced in excess when antioxidant systems are not working efficiently (40)

In contrast, the Low-responder group exhibited an increased abundance of butyrate-producing and nutritionally adaptive species (e.g., Eubacterium ventriosum 71 and Roseburia inulinivorans 72 )

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