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Measurement of the constituents of one-carbon metabolism and related pathways by LC-MS/MS (49, 146) provides a useful picture of the impact of low B6 status in analysis of plasma and parallel studies with cultured cells (48, 49)

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In another alternative, a compound of Formula (I) can be administered just followed by and any of the agents described above, or vice versa

Collectively, these results suggested that, within our experimental framework, FAT-7 expression likely functions as an indirect proxy for lifespan regulation rather than a direct determinant