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Regarding gene expression, SOD3 mRNA expression was found to be upregulated in patients with advanced MASLD as compared to those with mild MASLD

Eur J Pharm Sci 57:8797

It is believed that the knockdown of CD38 mediates a significant change in aerobic metabolism, including mitochondrial respiratory capacity enhancement, NAD + boosting and Ca 2+ transport

GSH concentration was measured using the Glutathione Assay Kit (Sigma-Aldrich) according to the manufacturers instructions

Morroniside, loganin, oleanolic acid, ursolic acid, and 7- O -galloyl-d-sedoheptulose exhibited the similar efficacy compared with the conventional oral hypoglycemic drugs (acarbose and metformin)