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Nature 583 (7816), 441446

doi: 10.1016/j.ijcard.2012.03.172 Influence of carbohydrate on serum caffeine concentrations following caffeine ingestion

doi: 10.1111/febs.14291

It is possible that genetic alterations that change the permeability of the bloodbrain barrier (BBB) could either increase the accumulation of toxic substances in the brain or make it possible for toxic substances to enter the brain that are normally kept out