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In a 2-year trial involving patients with type 2 diabetes mellitus (T2DM) and high cardiovascular risk, more events of diabetic retinopathy complications occurred in the patients treated with semaglutide injection (3%) compared to placebo (1.8%)

The longer needles create more significant micro-injury requiring extended recovery

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Dosing & Reconstitution Guide Educational guide for reconstitution and daily dosing Standard FDA-Approved Protocol (3.0 mL = ~3.33 mg/mL) Frequency: Inject once daily subcutaneously, preferably in the evening to coincide with nocturnal GH release [5] [6]