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Activity-dependent regulation of MEF2 transcription factors suppresses excitatory synapse number

Patients admitted in the Intensive Care Unit were excluded to avoid transient elevations of vitamin B12 due to hemodynamic, infectious, or metabolic changes

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In preclinical models of neuropathy, ARA 290 has been shown to prevent and improve peripheral neuropathic pain, an action that requires the innate repair receptor (25)