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For example, in a multicenter, randomized, double-blinded, and placebo-controlled trial involving 98 dyslipidemic patients, daily supplementation with 500 mg of amla extract twice daily for 12 weeks led to significant reductions in TC, TG, LDL, and the atherogenic index

Ashwagandha (i) can improve mitochondrial energy levels and functioning and decrease the activity of the Mg2+-dependent ATPase enzyme that breaks down ATP in terms of energy generation [156], and (ii) can raise creatine levels, which may then trigger the production of ATP [62]

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Currently, there are no medications specifically approved for the underlying fat accumulation of NAFLD

For example, PLGA-PEG nanoparticles, modified with antibodies or ligands for nasal delivery, can significantly enhance the ability to cross the blood-brain barrier and blood-nerve barrier (Maher et al., 2023)