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Next to platelet activation, TF release, through a process of NLRP3 inflammasome induced pyroptosis, is recognized as important driver of micro-thrombosis, in confluent with the emerging role of NETosis

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METRNL attenuates lipid-induced inflammation and insulin resistance via AMPK or PPARdelta-dependent pathways in skeletal muscle of mice

AOD-9604 is often marketed online as a 'fat-loss peptide.' The honest story is more of a cautionary tale: it was built to be a weight-loss drug, tested in people, and largely didn't deliver so it never became an approved medicine