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By contrast, Wilson disease patients continuously absorb copper from their diet but lack effective mechanisms to regulate intestinal copper uptake or excrete excess copper [19,20,27,44,59,70]

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This substantial reduction in endogenous Pure Copper peptide production directly correlates with the visible manifestations of skin aging, including decreased elasticity, diminished barrier function, increased transepidermal water loss, and reduced capacity for wound healing and tissue repair

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