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190 A meta-analysis of nine clinical trials published in 2020 found that acupuncture significantly improved AHI, daytime sleepiness, and oxygen saturation, particularly in patients with moderate obstructive sleep apnea

In some individuals, usually adults, acetaminophen can induce a high-anion-gap metabolic acidosis secondary to 5-oxoproline (ie, acquired pyroglutamic academia), possibly because of a genetically determined propensity (54

doi: 10.1128/msphere.00669-23 [DOI] [PMC free article] [PubMed] [Google Scholar] 52.Veeravalli K, Boyd D, Iverson BL, Beckwith J, Georgiou G

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The modifier subunit of Drosophila glutamate-cysteine ligase regulates catalytic activity by covalent and noncovalent interactions and influences glutathione homeostasis in vivo