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For example, in work by Jiang et al, a possible negative regulation of TGF1 (transforming growth factor beta 1) by Nrf2 activation was observed, raising the question of whether Nrf2 negatively regulates TGF1 expression by direct binding to the promoter region of its gene or by other, downstream effects

Hung TH, Huang SY, Chen SF, Wu CP, Hsieh TT

10.1155/2022/1582432 6 BainsA.KohrmanS.PunkoD.FricchioneG

424 All these reveal the potential of therapeutics against cellular apoptosis in ischemic stroke

In the case of autoimmune thyroid disease, removing the thyroid with a thyroidectomy eliminates thyroid antibodies, as there is nothing left to attack