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[0352] For direct administration to the sinuses, the pharmaceutical compositions described herein may be administered using, e.g., a microcatheter (e.g., an endoscope and microcatheter), an aerosolizer, a powder dispenser, a nebulizer, or an inhaler

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Together, this means rapidly activated efficient compensatory pathways and the ligation stop at the inferior caval vein efficiently bypassed (Vukojevic et al., 2018)

The highest weight loss was observed in the combination group of cagrilintide + semaglutide (-15.6% from baseline), with cagrilintide alone resulting in -8.1%, and semaglutide alone achieving -5.1%