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289 , F420F430 (2005)

SIRT3 physically interacts with FOXO3 in mitochondria and promotes the transcriptional activity of FOXO3A 35

TB-500 has been shown to promote cell migration, angiogenesis, cytoskeletal reorganization, and anti-inflammatory signaling in preclinical models 1,2

10.1021/acsmedchemlett.1c00561 33 CharaschanyaM.MaskreyT

Research has shown it stimulates growth hormone release without significantly affecting cortisol or prolactin, making it one of the most selective GH secretagogues available