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These data may point to the need to optimize the timing windows for the introduction of pro-remyelination therapies in demyelinating diseases such as MS, and may serve as a basic reference system for future studies of the effects of any intervention on demyelination and remyelination using the CPZ model

A summary of these recommendations is listed in Table 3

These tests may include 25 : Complete blood count (CBC) to screen for anemia and conditions affecting red or white blood cells or platelets Comprehensive metabolic panel to check kidney function and general health status Erythrocyte sedimentation rate (ESR) and/or C-reactive protein (CRP) to screen for inflammatory disorders Thyroid stimulating hormone (TSH) to rule out thyroid disease 25-hydroxy vitamin D to identify cases of deficiency Ferritin to assess iron status, especially in those with fatigue, cognitive dysfunction, restless leg syndrome, or a high risk of deficiency Vitamin B12 to test for deficiency, especially in cases involving cognitive dysfunction Various additional blood tests may be ordered when indicated to rule out other suspected diagnoses, such as autoimmune diseases, muscle diseases, neurologic disorders, and infections

After a month, looking back over those notes often reveals a clear upward trend that you would not have noticed in the moment

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