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*Correspondence: Jianmin Liang, [email protected] Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

Safety Toxicity The Food and Nutrition Board did not set a tolerable upper intake level (UL) for thiamin because there are no well-established toxic effects from consumption of excess thiamin in food or through long-term, oral supplementation (up to 200 mg/day)

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Conversely, upregulation of SLC39A14 in hepatocyte-specific TFR knockout mice leads to ferroptosis due to excess iron, making them more prone to liver fibrosis

During the financial crisis in 2008, Wells Fargo had to cut its dividend dramatically