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Under aerobic conditions, pyruvate formed as a product of glycolysis goes through oxidative decarboxylation, a process that removes a carboxyl group as CO 2 to form acetyl coenzyme A (acetyl-CoA), the typical starting molecule of the TCA cycle [4]

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Wound-healing and transwell assay B16F10 and 4T1 tumor cells were cultured in 12-well plates at a density of 3 10 6 cells per well