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5.2.2 Targeting ammonia death to enhance ICI efficacy ICIs have emerged as revolutionary therapeutic strategies in tumor immunotherapy, primarily by activating T cells and alleviating immunosuppressive signals (181)

Conclusion: Our findings indicate that HDL-centric lipidomic markers, particularly those within the larger HDL subfraction as well as acetoacetate, may differentiate MetALD from MASLD

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These enzymes use glutathione (GSH) as reductant (22), catabolized peroxides to the corresponding alcohols

In addition, the metabolism of MAs is also highly associated with the physiology, virulence, and pathogenicity of Mycobacterium [36, 37, 53, 54]