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However, due to its low specificity, this method received a lot of criticism [Frijhoff et al ., 2015]

BioPython: freely available Python tools for computational molecular biology and bioinformatics

Accumulation of adherent mucus plaques and plugs compresses the periciliary layer, slows or abolishes mucociliary transport, and creates a nidus for bacterial colonization and infection [9, 23]