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Co-Immunoprecipitation Co-immunoprecipitation was performed using Invitrogen TM Dynabeads TM M-270 Epoxy beads (ThermoFisher Scientific) bound to anti-BNIP3-antibody 1C8 or anti-BAX antibody (2D2, Cell Signaling Technologies) (according to the manufacturers instructions (Invitrogen TM Dynabeads TM Co-Immunoprecipitation Kit, ThermoFisher Scientific)

Dimitrow PP, Rajtar-Salwa R (2016): Obstructive Form of Hypertrophic Cardiomyopathy-Left Ventricular Outflow Tract Gradient: Novel Methods of Provocation, Monitoring of Biomarkers, and Recent Advances in the Treatment

Moreover, the decreased mucociliary clearance in the respiratory tract, combined to the defective ion transport allows the proliferation of Pseudomonas aeruginosa as well as other pathogens in the respiratory tract which become more and more resistant due to iterative treatments and result in a repetitive inflammatory response (114)