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TUDCA may be useful in cases of sluggish bile or when fat is less easily managed , particularly with age

In light of these findings, it has been concluded that tobacco smoking is associated with a significantly increased risk of advanced and more severe disease in the form of pulmonary cavitation, positive sputum smear and culture results, and lower conversion rate after treatment initiation (Mahishale et al., 2015)

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(41) which used approximately 520 participants, most of the studies that did not observe any significant results used a very low sample number, indicating this could have affected the power of the results