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GSH-driven metal reduction In catalytic or metal-complex systems, oxidation of GSH to GSSG can be coupled to transition-metal redox cycling, thereby supporting electron transfer processes involving Cu 2+ /Cu + or Fe 3+ /Fe 2+ couples 179,180

Ferroptosis is a novel form of PCD, which exhibits several pathophysiological features reminiscent of those seen in SLE, including intracellular iron accumulation, mitochondrial dysfunction, lipid metabolism disorders, and regulation by DAMPs ( Table 1 )

Hepatitis Viral infections or autoimmune conditions that cause liver inflammation