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R152 and active site residues C46, K48, Q81, and W136 are highlighted and shown as sticks

The diagnosis is applied to legal qualification for benefits and income under disability insurance and to eligibility for social security and workmans compensation benefits

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*Correspondence: Lei Xu, [email protected] Liu, [email protected] These authors have contributed equally to this work This article was submitted to Cellular Neuropathology, a section of the journal Frontiers in Cellular Neuroscience Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers