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Consequently, they can proliferate and go undetected in cell culture dishes for a long period of time, becoming a major obstacle to performing reliable and accurate in vitro experiments

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Discuss the mechanism for how this elution step works and give three possible disadvantages with this purification method

10.1002/ana.410050105 226 PringleN.CollariniE

These changes are associated with reduced affinity for IGF-binding proteins and a prolonged active duration in experimental models