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Moreover, a high percentage (almost 30%) of these patients exhibit idiopathic anemia (77) that may be caused by blood loss due to repetitive blood tests and surgical interventions, as well as occult bleeding (mainly in the gastrointestinal tract) during hospitalization

doi: 10.1111/nph.15989 67 SarkarT

In the context of IgG-mediated autoimmune diseases, FcRn maintains high levels of pathogenic auto-Abs in the circulation and tissues via a cellular recycling process that extends the plasma half-life of IgG Abs