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High ATP demand, in combination with dysfunctional mitochondria, make these neuron groups more sensitive to degeneration (Wang and Michaelis, 2010)

380 Vorinostat also reduces human immunodeficiency virus (HIV) replication through autophagy activation in infected macrophages without cytotoxicity, 350 supporting the findings of clinical trials for HIV latency reversal (such as NCT01365065, NCT01319383, NCT01933594, and NCT01680094)

Ito cell tumorlarger and more extensive than hyperplasia